Hi Kishore,
As far as I have understood age is the most important variable when they look at results of stem cell transplantation. Look at page 37 in this guidebook about MDS:
http://www.aamds.org/aplastic/files/dms/MDSGuide.pdf
I have read results from trials where older patients have has a SCT but I don't think any patients have been 78 yo.
Before SCT they try all kinds of drugs - most of them much stronger and more toxic than decitabine.
Kind regards
Birgitta-A