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Old Sun Apr 24, 2016, 09:31 AM
BeachyGal BeachyGal is offline
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Join Date: Apr 2016
Location: USA
Posts: 1
M Spikes, Kappa/Lambda High, MCV High and More (help)

Hello ~

My PCP found a m spike which led to a hematologist. Three appts later (every three months for bloodwork) and I still don't know what the heck is going on.

I will share labs in hopes anyone else may have traveled down this same path.

To date, a trace monoclonal IgM protein w an imbalance of light chains with mild cryoglobulemnia.

IgM - 522. Normal range is 35-290
Total Protein - 6.4. Ref range is 6.6-8.9 g/dl
Kappa free serum - 4.90. Ref range is 0.33-1.94 mg
k/l flc ratio - 2.93. Ref range is 0.26-1.65
MCV - 101.3 (high)
MPV - 6.2 (low)
Absolute lymphocytes 1.0 (low)
Macrocytosis- slight

I had BMB showed B cells but not enough for a lymphoma diagnosis. A ct scan showed two lung nodules and a repeat six months later showed the nodules were stable.

I'm ok if the hematologist is not concerned EXCEPT I feel like crap. No energy, night sweats. He is going to refer to rheumatologist for autoimmune disease now.

Anyone else out there similar to me or can you provide any helpful input.

Thank you so much.
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