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Neupogen for patients with MDS
Hi Neel,
I've had MDS for 7+ years, started Raeb-1, quickly Raeb-2 at 14% blasts.
Taking Neupogen is somewhat controversal with some doctors recommending it but others not.
I've taken Neupogen on and off over the entire 7 years of my successful treatments. My doctor feels it helps to increase the WBC and ANC and in my case I've always responded to Neupogen. Two other MDS centers of excellence both recommended that I could take 1 Neupogen per week.
Studies have shown that if one is taking Procrit or Aranesp to stimulate red blood cell production taking Neupogen at the same time can increase the success rate of the red blood cell stimulants.
I only take the Neupogen if the ANC is less than 500 (or .05 depending on the scale being use to measure ANC).
Over the years I've had 100's of Neupogen shots and yet remained successful in fighting MDS.
Everyone is different so each patients response will be different.
Hope this helps a little.
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Kirby71, RAEB2 dx 2/04, Thalidomide 30 mo, Revlimid 18 mo, No resp Vidaza
6/09 2nd Thalid use, Promacta, Lowdose Dacogen added 10/09 at 40% blasts. 5/11 BMB-blasts 8%.
2/11 2nd Revl restart=good resp, Platelets drop 6/11, 3rd Thalid,+Nplate+Dacogen. 7/12 Cnts stable for 10 mo.
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