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Hypocellular marrow is rare for MDS. It is not a unique classification. So, a patient can be RA, for example, with a hypocellular marrow. A hypocellular marrow is more common in "younger" MDS patients (under 70). It is easy to confuse with aplastic anemia and also is more likely to respond to immune suppressant treatments.
AngieA, if your husband only has trisomy 8 and has a hypocellular marrow, you should discuss with his doctors trying immune suppressant therapy (ATG/Cyclosporine or Campath). Trisomy 8 is thought to be another marker that an immune attack is occurring. So, he may be a good candidate for the treatment.
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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