|
Hypocellular bonemarrow
Hi Sandi,
Hypocellular bone marrow means too few cells in the bone marrow according to the patient's age. Hypercellular is more common in MDS as Hopeful wrote. As far as I understand the cellularity has no prognostic value – I have hypocellular myself.
Paul’s doctor is using the IPSS for MDS (International Prognostic Scoring System)
They look at
1) % of blast cells in the bone marrow: <5% score 0 5-10% score 0.5 11-20 score 1.5 and 21-30 score 2
2) Karyotype: Good score 0 Intermediate score 0.5 and Poor score 1
3) Cytopenias: 0-1 score 0 2/3 score 0.5
Karyotypes means chromosome types
Good: normal, -Y, del(5q), del(20q). Poor: complex (≥ 3 abnormalities) or chromosome 7 anomalies. Intermediate: other abnormalities.
Cytopenias
means low counts for example Hemoglobin <10.0, Neutrophils (a type of WBC) <1.8, platelets <100
Low risk 0
INT-1 0.5-1.0
INT-2 1.5-2.0
High risk ≥2.5
Kind regards
Birgitta-A
73 yo, dx MDS Interm-1 2006. Good results with Thalidomide + Prednisone since 2010
|