I just happened to find these abstracts/articles. It looks like Aparna Prasad & David O Carpenter of University of Albany (with co-authors) published three papers in 2010 & 2011 showing the Omega-3 and Omega-6 Fatty Acids kill thymocytes, at least in mice, and that the effect is lessened if you add Vitamin E. (A lot of companies add Vitamin E to their fish oil to reduce oxidation/rancidness, but it looks like if you want full effect you don't want to take vitamin E with your fish oil.) As a disclaimer/warning, both thin the blood at high doses. You don't want to take very high doses of either fish oil or vitamin E individually or together if you have very low platelets. I find this fascinating. I'm tempted to email the authors to see why they decided to study this and see if they respond. I'm not advocating that people try using fish oil instead of ATG and Cyclosporine for Aplastic Anemia. Instead, it would be very exciting if the EPA & DHA in the fish oil can protect your kidneys from the nephrotoxic effects of the Cyclosporine WHILE enhancing the effect of the ATG.
Role of calcium and ROS in cell death induced by polyunsaturated fatty acids in murine thymocytes.
http://www.researchgate.net/publicat...es?ev=auth_pub
Full article available for free.
Omega-3 and Omega-6 Fatty Acids Kill Thymocytes and Increase Membrane Fluidity
http://www.researchgate.net/publicat...ty?ev=auth_pub
Full article available for free.
Mechanisms of cell death of thymocytes induced by polyunsaturated, monounsaturated and trans-fatty acids.
http://www.researchgate.net/publicat...ds?ev=auth_pub
Only abstract available.