Here we are, finally "discovered", from 3 July 2014:
http://www.sciencedaily.com/releases...0703162338.htm
Biochemical cascade causes bone marrow inflammation, leading to serious blood disorders
"The molecular cascade leading to inflammation was not occurring directly in the bone marrow cells that produce blood cells, but in cells of the bone marrow microenvironment, especially in endothelial cells that line the capillaries -- tiny blood vessels -- inside the bone marrow. This was a key discovery, Dr. Carlesso said."
i.e. inflammation. My son's Henoch–Schönlein purpura (HSP), which occurred immediately preceding his Aplastic Anemia, is inflammation of the capillaries in his legs. I am convinced he has HSP of the bone marrow (it can settle in other organs. When it settles in the kidneys it is called IgA Nephropathy.)
Important for reading the previous article.
myeloproliferative disorders:
http://en.wikipedia.org/wiki/Myelopr...note-Tefferi-2
"The myeloproliferative neoplasms (MPNs), previously myeloproliferative diseases (MPDs), are a group of diseases of the bone marrow in which excess cells are produced. They are related to, and may evolve into, myelodysplastic syndrome and acute myeloid leukemia, although the myeloproliferative diseases on the whole have a much better prognosis than these conditions."