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Cheryl.
Thanks for the reply and suggestions. The engineer in me has always made me shy away from stuff that isn't proven. I am sure it helps a great number of people but I like to stick with drugs that have gone through rigorous testing and have been proven to be beneficial. Thanks for the suggestions though.
Paul,
A couple lines out of my biopsy were:
“Hypocellular marrow (10 - 15%) with trilineage hematopoiesis , relative Erythroid hyperplasia with dyspoiesis , and decreased megakaryocytes.”
“Bone marrow is now markedly hypocellular (10 - 15%) with rare megakaryocytes and some dyspoietic changes noted in the erythroids along with mild erythroid hyperplasia, along with damage appearance”
Chimerism was at 100% donor the day of the biopsy.
The doc has never mentioned the spleen. I have heard of the spleen sequestering platelets but would that cause the WBC and RBC counts to tank also?
There was no increase in blast (1%)
The doc specifically said it wasn't a transplant failure but could be a graft failure - all be it a late one.
Thanks again for the comments & concern
Data
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Prostate Cancer: Treated in early 2013 with HDR Brachytherapy. MDS-RCMD: Oct 2014. Biopsies: 46,XY,t(7;18)[2]: 46,XY,del(7)( q22)[3]: 45,XY,-7[6]: 45,XY,-7[10]: 45,XY,-7[13]. HSCT in April 2016.
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