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thalidomide working ?
My father has been taking thalidomide 100 mg for last 4 months (since 22 april, 2011). he was transfusion dependent when he started thalidomide, required both platelet and blood. After arnd 15 days of start of thalidomide , his counts stablized , there wasnt any marked improvement, but the counts were stable and remained so till today i.e. 17/8/11, i.e. Hb moved slowly till 11, Platelet rose staidly till 40000, then came back to 30000 and remained between 30000-40000, TLC arnd 2000-2400. Howeve todays report shows Hb and TLC as same i.e 10 and 2400 resp, however his platelet count has taken a beating i.e. 18000. Any inputs and what to do ?
Moreover he stopped taking thalidomide for arnd 1 week i.e. 3-8-11 till 10-8-11 due to extreme weakness caused by it. However he started it since 10-8-11.
Is the fall due to discontinuation of thalidomide ?
Has thalidomide stopped working ?
Will thalidomide show its effect later ?
regards,
neel
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Father age 64 diagnosed with MDS RAEB-2, with 15%-18% blasts in October 2010. Only had blood and platelet transfusions. Ayurvedic treatment which showed result for arnd 5 months. Started Tahlidomide 100 mg started on 22 nd April 2011. Revolade 50 mg started on 2 nd april 2012.
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