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Hi Lisa and pvinod,
I remember from one of the conference speakers that Rabbit ATG is typically used for salvage treatment because of the fear that a patient may have a more severe reaction to the therapy the second time around (like anaphylaxis shock). One of the people in the audience commented that this had happened to her! There haven't been official studies comparing the two at NIH.
The response rate to a second course of ATG in a non-responder is about 1 in 3 - not as common as the first course, but still possible.
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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