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Old Tue Aug 16, 2011, 12:52 PM
Hopeful Hopeful is offline
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Join Date: Jan 2009
Location: California, USA
Posts: 766
Sorry to confuse you further.

ATG/CyA is the standard first treatment for older patients with SAA.
MAA usually gets a watch-and-wait approach, unless things start changing or the patient becomes increasingly transfusion dependent. This is because the marrow can sometimes spontaeously recover on its own. Also, it could be because the diagnosis of AA is based on elimination of every other possible diagnosis. So, first the doctors like to make sure that you really have SAA before they give you toxic drugs to treat it! Your counts aren't that bad (in the AA/MDS world). I was on watch-and-wait for a while with lower counts than yours.

I was just theorizing that Cyclosporine alone may have a place in the treatment of this disease for people with MAA. It was tried at one point for me, but I had gone too far past "the point of no return". Had it been tried earlier, I wonder if I could have avoided ATG and the MDS evolution.

Good luck with your blood test!
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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