Quote:
Originally Posted by Hopeful
I currently take Gengraf. I tried Neoral, but my trough was actually lower with that.
I usually take it with water about 1-2 hours after eating. I don't eat anything afterwards. I've read that this increases the concentration in the blood.
Does this seem correct?
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Hi Hopeful,
Yeah, you seem to be doing all the right things. When you are saying that your kidneys don't like it anymore, what do you mean? Do you have elevated creatinine, BUN, high blood pressure?
I was asking about food because there are many studies that show that taking CsA with fatty foods or grapefruit juice increases the amount of CsA in the blood stream (more CsA gets absorbed from the gut). That would presumably allow for a smaller overall dose to get to the same through levels. However, your kidneys process the CsA that gets in the blood stream, so I'm not sure it would help.
Sandra