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Old Sat Jun 13, 2009, 12:23 AM
Hopeful Hopeful is offline
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Join Date: Jan 2009
Location: California, USA
Posts: 766
Question Cyclosporine dosage and troughs

Hi,

I'd like to take a poll on what cyclosporine dosage people are taking (per kg/day) and the corresponding trough reading.

I'm wondering if there is anybody else with a crazy metabolism like mine!

To achieve a trough of 200, I need a dosage of 8 mg/kg/day (!)
My kidneys can no longer tolerate this. So, I'm back down to 5 mg/kg/day. Now my trough is around 80

I'd be interested to here what others are experiencing.

Thanks!
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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