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Hey Neel!
Here's a post I wrote about one theory of using immunosuppression (ATG is an immunosuppressant) for MDS. It definitely works for some patients; the researchers are still trying to figure out how to tell, in advance, which folks it is most likely to help.
It is less commonly used in MDS than AA, I think. I wonder if Sue is maybe having it because she also has PNH?
When it is used to treat MDS, the data pretty conclusively shows that it's more effective when combined with a follow-up regimen of cyclosporin (another immunosuppressant). Neither is as effective alone.
Other folks are better equipped to answer your questions on how its administered, etc., because I haven't actually had it.
Take Care!
Greg
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Greg, 59, dx MDS RCMD Int-1 03/10, 8+ & Dup1(q21q31). NIH Campath 11/2010. Non-responder. Tiny telomeres. TERT mutation. Danazol at NIH 12/11. TX independent 7/12. Pancreatitis 4/15. 15% blasts 4/16. DX RAEB-2. Beginning Vidaza to prep for MUD STC. Check out my blog at www.greghankins.com
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