Hi Steve,
As far as I understand Thalidomide is not up to date today. There are hardly any studies reported since 2011. Experts don’t recommend Thalidomide for MDS.
http://www.croh-online.com/article/S...139-4/abstract
My doctor was surprised when I responded so well (more than 2.5 years) on that drug. In most studies they gave the patients 800 mg/day and they got severe adverse effects. I responded on 50 mg 4 days/week. Kirby Stone responded well too.
I don't think there are any studies that show positive results for Revlimid as monotherepy in high risk MDS. Vidaza shows much better results with about 50% responding and is recommended as first drug for high risk patients.
Then the combinations of Revlimid with for example Vidaza show up to 72% response in high risk patients.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525020/
Hi bailie,
Hope for positive SCT results!
Kind regards
Birgitta-A