Hi Linda,
Good that Al is feeling OK! You know nausea is a quite common adverse reaction. When his WBCs are low he has to be
very careful and try to avoid infections both from other persons and from food.
Here is an article about Sapacitabine. As you can see most of the 47 patients have AML – only 4 have MDS.
If you look at Table 3 at adverse effects concerning the counts (hematologic) for the 35 patients who received Sapacitabine 7 days a week you can see that only one patient developed low HGB grade 3-4 (serious).
One patient got low WBCs (leukopenia) grade 1-2 (not serious) and 6 serious.
One patient got low platelets (thrombocytopenia) not serious and one patient serious.
http://jco.ascopubs.org/content/28/2/285.full.pdf
This means that low counts are not very common. Hopefully Al will respond to supportive treatment. If his WBCs are very low they perhaps could give him Neupogen if that drug is OK in this trial.
Kind regards
Birgitta-A