[Chirley]

Hi Scott,

It's great that your Dads counts are so good, now he just has to feel a bit better to appreciate the respite from transfusions and chemo.

I found this which sounds just about what you are describing.

Diabetes insipidus (DI) is a condition characterized by excretion of large amounts of severely diluted urine, which cannot be reduced when fluid intake is reduced. It denotes inability of the kidney to concentrate urine. DI is caused by a deficiency of antidiuretic hormone (ADH), also known as vasopressin, due to the destruction of the back or "posterior" part of the pituitary gland where vasopressin is normally released from, or by an insensitivity of the kidneys to that hormone. It can also be induced iatrogenically by various drugs


If your Dad has this and can't drink enough to cover the urine output he could have mild dehydration. This would explain the cotton mouth, weakness, metal taste.

I also read where diabetes insipidus can be caused by haemachromatosis (too much iron).

Anyway, just a thought.

Best of luck.

Chirley