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Old Wed Sep 26, 2012, 09:46 PM
ConfusedSpouseInFlorida ConfusedSpouseInFlorida is offline
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Join Date: Mar 2012
Location: Florida
Posts: 4
CMV+ donor for a CMV negative recipient SCT

Hello -
Your messages and threads have helped me tremendously in the last two years as my husband and I have travelled through this journey.
He was diagnosed with MDS (RA) 18 months ago. After an awful experience with ATG, he actually was doing quite well (relatively speaking) for several months. Imagine our shock returning for a BM biopsy in April and learning his blasts had jumped from less than 5% to 18% (putting him at RAEB-II). We were told to plan on a SCT after 4 months of Vidaza. We were set for transplant, when the biopsy in August showed no change in blasts.
My husband just spent 4 weeks at Moffitt receiving CLAG chemo. His blasts are down to 3%, with another biopsy scheduled for Monday.
We are to move to SCT (unrelated donor) early October.
Today, we learned my husband is CMV negative, and our 10-for-10 match donor is CMV +.
We got nervous last night researching the possible complications from this imbalance (death, coma, blindness, encephalitis, hepatitis, etc.).
Any comments or thoughts on this?
ConfusedSpouseInFlorida
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