ConfusedSpouseInFlorida,
Transplant doctors will try to avoid having a CMV-sero-positive donor and CMV-sero-negative recipient if there's another donor available. But that's not always the case.
If there isn't a better choice for your husband, because there are no other matched donors or they are less of a match or otherwise riskier, they can proceed. In that case, your husband's transplant doctors are likely to give him drugs to help prevent CMV from activating, and they will test him frequently for CMV infection so he can be treated promptly if it occurs.
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