View Single Post
  #6  
Old Sun Jan 22, 2012, 06:01 PM
knstone knstone is offline
Member
 
Join Date: Aug 2006
Location: Cincinnati, OH
Posts: 118
Hi Cheri

I've had blasts show up in the blood on only 2 occasions over nearly 8 yrs, and for one week only. The last instance showed 3% blasts in peripheral blood, but a BMB the following week only showed only 5% blasts and CBC that week had no peripheral blasts. One MDS doctor said if they don't show up in consecutive CBCs over 2-3 weeks it may not be serious. Neupogen can increase the number of immature cells (blasts) and some can get into the blood stream on occasion.
With MDS/AML the WBCs are generally low, 2.2 is still low so it would not seem to indicate a transformation to leukemia (AML). A BMB that shows high blasts in the marrow is a more telling sign of a transformation of MDS to AML.
Hope your success in controlling MDS continues.
__________________
Kirby71, RAEB2 dx 2/04, Thalidomide 30 mo, Revlimid 18 mo, No resp Vidaza
6/09 2nd Thalid use, Promacta, Lowdose Dacogen added 10/09 at 40% blasts. 5/11 BMB-blasts 8%.
2/11 2nd Revl restart=good resp, Platelets drop 6/11, 3rd Thalid,+Nplate+Dacogen. 7/12 Cnts stable for 10 mo.
Reply With Quote