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Ken,
You are correct that a large number of transfusions can be a disadvantage for a subsequent transplant. I think it interferes with the engraftment process. All blood products you get should be irradiated and leukocyte-reduced. That's a good idea for anyone getting regular transfusions, but especially for those who may get a transplant.
Have you considered going to the MD Anderson Cancer Center, at the University of Texas in Houston, for a second opinion? They can assess the risk of getting these transfusions when a transplant is a possibility. Even if they confirm that your doctor's approach is the best choice for now, you'll have more confidence in your treatment plan having heard from another expert.
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