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Answer to Debbie
Dear Debbie,
Well, I have MDS TOO. And have just about the same questions you have. They are presently treating me with Vidaza. Have not had a transfusion since last May. I hope this info. can help you. I also get very depressed. But I noticed that when I exercise (eg. walk on my treadmil for at least 10 minutes twice a day) it helps my depression and makes me feel physically better.
Best regards, and best of luck for all of us.
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Anne, diagnosed MDS 12/06; treated with Vidaza, procrit, transfusions 
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