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Mike,
I think you are smart to hold out as long as possible for transplant. There is excellent statistical research that shows transplant for MDS results in better overall survival when undertaken close to the point of transition to AML.
And, as you say, the transplanters get smarter every year. In my recent visit to NIH, when we discovered that I have transitioned from low risk to very high-risk MDS, it was clear that the doctors there respect that research. Dr. Townsley spoke about a "sweet spot" for transplant. And that is when you transition from low risk to high-risk.
As you know, every case of MDS is different, so that advice may not apply to every individual. But on average, it seems to be good advice.
Take care!
Greg
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Greg, 59, dx MDS RCMD Int-1 03/10, 8+ & Dup1(q21q31). NIH Campath 11/2010. Non-responder. Tiny telomeres. TERT mutation. Danazol at NIH 12/11. TX independent 7/12. Pancreatitis 4/15. 15% blasts 4/16. DX RAEB-2. Beginning Vidaza to prep for MUD STC. Check out my blog at www.greghankins.com
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