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Old Tue Feb 4, 2014, 07:47 AM
Mseth Mseth is offline
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Join Date: Sep 2013
Location: New Delhi, India
Posts: 186
Fever during/after transfusion

Hello all,

Need some advice from others receiving red cell transfusions.
Every once in a while, my mother develops a fever after transfusion. She receives 2 units at one time. Sometimes the fever comes on towards the end of the 2nd unit, or sometimes the next day. A few months back the fever persisted for a week, she was put on antibiotic at that time. Normally a paracetamol or an advil(ibuprofen) brings it down. I have read that fever is the most common side effect after transfusion, and the daycare doctors say it is normal. But is there any premedication that can help? She receives leucoreduced pRBC, she can also get leucodepleted pRBC, but develops some unexplainable high potassium levels when she gets the leucodepleted ones.
Her WBC are normal and she has rarely ever had fevers/chills in her lifetime.

Thanks for any advice.
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Mother age 79, dx MDS RCMD low risk del 20q April 2013, no response to EPO, Danazol. pRBC tx dependent - 2 units every 3-4 weeks, exjade Dec 2013 - Mar2014, restarted Dec 2014
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