AMG 531/Romiplostim/Nplate is a new drug (perhaps approved by FDA July 23 2008), that increases platelets. There are several trials for MDS patients but one study showed that 22 of 44 MDS patients had increases symptoms with more blast cells or AML
, so I think all patients with MDS should avoid this drug. There are better drugs for low platelets in the pipelines
.
http://www.fda.gov/OHRMS/DOCKETS/ac/...FDA-Lemery.ppt
Kind regards
Birgitta-A