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MDS to AML
Contact with nurse practicioner at the cancer clinic who related info from my doctor that the pathologist indicates that this could be progressing to AML. She indicates that the hydrea at one dose of 500mg per day should start lowering the WBC and the blasts in the peripheral blood and the bone marrow. I posed the question that if three rounds of Vidazza didn't reduce the blast in the bone marrow how could hydrea lower the blasts in the bone marrow. She indicated that it would. I'm not so sure.
WBC today at 41 x10^9/L up from 37 on the 25th x10^9/L
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Wife 63, June 2010 MDS (refr anemia - excess blasts type-2) PLTs 11,000/μl with giant forms 2 TF/wk. Hgb kept at 80g/l with 1TF per 2 weeks. 9% blasts 2 cytogenic abnormalities del(5)(q22q35) + inv(20)(p11.23q11.21) 3 cycles Vidaza no effect. June 2011 to AML WBC to 67 blasts and Aur rods in blood.
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