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Hi Markley,
Just to put you a little at ease, the WBC have the most variance of any cell line. They have a very short life cycle. I've had jumps like this on weekly CBC's. It is nothing to be alarmed about. Any inflammation, virus, or infection (even one you may not realize that you have yet) can affect the WBC/ANC.
Now, if your doctor is concerned enough to monitor you monthly, and you see that you have a continued downward slide in your ANC month-to-month, then maybe you could call it a trend. However, yearly variance in WBC/ANC is likely normal.
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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