Quote:
Originally Posted by Chirley
That doesn't sound quite right. I was severely transfusion dependant (3 units every two weeks) for a long time and I still had low B12. I need courses of B12 injections from time to time. Homocysteine levels can be high with folate deficiency rather than B12 deficiency so if the level is high there needs to be a clinical judgement as to which vitamin is deficient.
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Chirley, it did not sound right to me either initially, which is the reason the supplements were started, but with 500 mcg daily oral B12, moving from 200 to 1200 levels in 5 months seems strange. My mother has normal-mid/high folate levels, no supplements, she gets it from her diet i guess, but she has no dietary source of B12, so a high homocysteine would likely point to a B12 issue in her case.
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Mother age 79, dx MDS RCMD low risk del 20q April 2013, no response to EPO, Danazol. pRBC tx dependent - 2 units every 3-4 weeks, exjade Dec 2013 - Mar2014, restarted Dec 2014
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