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Cytogenetics
I'm pretty clueless when it comes to cytogenetics. I basically understand the additions, deletions and translocations etc but more in depth things like balanced translocations which may be occult etc, leaves me confused.
Having said this, bear with me if my interpretation of an abstract I just read is wrong.
I read a journal article from 2011 which appeared to say that 23% of people with confirmed MDS/AML and had normal BM cytogenetics on FISH were found to have chromosomal abnormalities when peripheral blood studies were performed.
If I have interpreted this correctly, why do they do cytogenetics on bone marrow? Is it simply because they are already there looking at the stem cells?
Regards
Chirley
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