View Single Post
  #6  
Old Fri May 8, 2009, 02:35 PM
Birgitta-A Birgitta-A is offline
Member
 
Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
Nplate (AMG 531)

Hi George,
You know both Nplate and Promacta/Revolade are approved but have restrictions so only patients with Immune Thrombocytopenic Purpura can get the drugs so far.
The FDA has a special warning about Nplate in MDS patients because the drug can make you disease worse (page 12) : http://www.fda.gov/cder/foi/label/2008/125268lbl.pdf
Promacta/Eltrombopag seems to decrease leukemia cells in tubes. A new drug LGD 4665 should be in trials for MDS and many other drugs for low platelets are in pipelines .
Kind regards
Birgitta-A
Reply With Quote