[knocksonce]

husband diagnosed w/ tx-related MDS in March. He is 70 years old. At time of dx was needing rbc transfusions every 2 weeks. Had 1st round of Vidaza 1st week of April.

Counts have dropped progressively since. Started needing rbc transfusion every third day and platelets about once per week. Had 2 units rbc on Thursday. Saturday night I took him to ER. His hemoglobin was 4.8 and platelet at 8000! Transfused 4 units rbc and 2 platelets. Yesterday platelets were 20,000.

Did 3 packs of platelets yesterday and an endoscopy of upper GI tract. No evidence of ulceration and only pinprick bleeds, probably spontaneous from 8000 platelet count. Still in hospital - no evidence of bleeding, but can't keep counts above critical levels.

Getting scared that counts will not rebound. Has anyone else here had counts this bad and come out the other side OK?