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Old Mon Dec 13, 2010, 01:13 AM
Hopeful Hopeful is offline
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Join Date: Jan 2009
Location: California, USA
Posts: 766
Quote:
Originally Posted by MK921 View Post
My doctor had said at one point that the cyclosporine may actually be keeping my counts low. Has anyone heard that before?
That is very interesting. I am 2 years post ATG and am still taking cyclosporine. Since about 7 months post-ATG, my platelets have slowly risen at a rate of about 3k every 3 months.

Last month, I cut my cyclosporine by a mere 25 mg because of kidney troubles, and low and behold, my platelets jumped 15k...in 1 month! I will have to wait until next month's labs to ensure this is not a fluke.

If you have the chance, please ask your doctor why he thinks cyclosporine may keep counts low. I have always wondered if the stress on the kidneys of cyclosporine causes a decrease in the TPO generated by the kidneys, which consequently decreases platelet production.
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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