Eltrombopag for severe AA
My husband (56 years, diagnosed with severe AA April 2012, one ATG treatment May 2012, only limited response, Ciclosporin since may 2012) has been taking Eltrombopag (Promacta in US, Revolade in Europe where we live) for one year now with encouraging results. Once he was on the full dosage counts began to rise significantly and now he has been platelet transfusion free for one year and transfusion (red blood)free for 3 months with good white blood cells counts too. Hospital here in Switzerland are monitoring closely and informed us at the start of treatment that long term studies for safety of this drug are still not completed. In this game though, as others on this forum have said, you have to "pick your poison" so to speak, so we decided to take the chance and were lucky that our health insurance funded it. I know that NIH in US have just completed one study on use of this drug for AA - findings to be published in Journal of Blood next month apparently.
Wish you lots of luck!
This forum is a wonderful resource and has helped us endlessly. Many thanks and all the very best to all.
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