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There have been a couple of trials out there that combine revlimid and azacitidine with pretty high success rates, and there is another with azacitidine and pracinostat that has had an 80-90% success rate in inducing remission. Not sure what the underlying requirements are, but there have been a couple of forum members on these as I recall.
So far as I know, revlimid alone has not been that successful in the absence of a del 5q, but has worked in up to about 30% of patients in the lower risk category without 5q.
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MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
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