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Thanks for that Tom, I'll keep the Cat scan idea in mind if I need any more bmbs. I have told my doctor that I don't want any more investigations (including bmbs) unless my blood tests suddenly change and get a lot worse. I'm happy just to keep having the blood transfusions, they aren't that much of an inconvenience compared to some of the other things that have been mentioned. It's interesting to hear that other people have hard or dense bone. I wonder if it's a coincidence or whether it's a sign of bone marrow problems? Any one else have this problem? Chirley
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