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Addendum: Platelets and Eltrombopag
After my ATG course, although the platelets were in the 100K range, actually they are now a mixture of normal size and large sized platelets. Initially they were not detected in hemogram machines, but new machines like the Sysmex 1000 detect these.
Large platelets are known to be more effective for clotting, but with eltrombopag, the effect on large platelets is to make them conjugated and create giant platelets, which can clog blood capillaries. This can lead to sudden heart attacks or brain haemhorrage in the long term. This is the reason I came away from the eltrombopag treatment.
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