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Old Fri Feb 11, 2011, 02:46 PM
mausmish mausmish is offline
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Join Date: Mar 2010
Location: Maryland
Posts: 453
Thanks, Birgitta! That was a very interesting paper, although I won't claim to understand all the details. I was pleased to see one of the conclusions on page 47:

"Azacitidine, also in high doses, has limited toxicity on normal bone marrow progenitors. In fact, clonogenic assays suggest a possible direct stimulatory effect of azacitidine on bone marrow progenitors. This supports the use of azacitidine maintenance after allogeneic stem cell transplantation to reduce the risk of relapse."

Karen
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Karen, age 62, dx MDS RAEB-2 1/8/10: pancytopenia WBC 2.7k/Hgb 7.4/Hct 22.1/Plt 19k; complex cytogenetics -3,del(5)(q14q33),-6,+8,+mar,17% blasts. MUD BMT Johns Hopkins 11/30/10. Dx tongue cancer 8/31/12. ok now. blog mausmarrow.com
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