I haven't had personal experience with Vidaza, but from what I have heard and seen, Vidaza can be an effective pre-treatment regimen for transplant. It also has been used successfully as part of some post-transplant regimens (for example, Robin Roberts who also had secondary MDS).
The one caution with Vidaza is that if you start it, you should be prepared to stick it out for at least 6 cycles before determining whether it has worked. If you stop sooner, it seems like things could go downhill faster.
Responders to Vidaza seem to have a pretty full life while it is working. Plus there is always the potential that new treatments/regimens will be discovered in the meantime - especially with the rapid evolvement of genomics.
Enjoy your granddaughter!
53 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent