Thread: Dacogen
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Old Fri May 20, 2011, 08:38 PM
Neil Cuadra Neil Cuadra is offline
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Quote:
Originally Posted by DanL View Post
I was not able to find the articles, but I know that I have read in a couple of different places that some people respond better to Vidaza than Dacogen, and others respond better to Dacogen than Vidaza. They are very similar, but there is enough difference to consider switching.
Results from studies continue to accumulate, sometimes across different patient populations. I spotted a study from 2009 that reported statistics favoring Vidaza over Dacogen. That was based on almost 1000 patients across four studies, but of course those studies were even older than this 2009 meta-analysis. Newer data may show other results, especially because treatment with these drugs has evolved (e.g, changes to dosing schedules). You also have to notice what they are measuring, e.g., response rates, relapse rates, or survival rates over a given length of time.

I suggest to patients that they ask their own doctors why they'd favor one or the other, and most importantly why.
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