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interesting and thanks to all for replies. His docs expressed concern today that he may not be strong enough for splenectomy, but sounds like there is good history of using this procedure to treat ITP. I would think that trying a standard treatment like vidaza would be a better way to start. A doc I work with also wondered if they have ruled out paroxysmal nocturnal hemoglobinuria as my fathers bone marrow is hypocellular, where it is more usual to have hypercellular bone marrow in MDS, from what I understand. Not sure if that has been done, but will check...
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