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Steve, It is my understanding (and I could easily be incorrect) that these mutations will not go away without having a stem cell transplant. That was my situation. After transplant I developed another mutation referred to as the "Philadelphia chromosome" which combined the 9 chromosome with the 22 chromosome (9;22). These appear to be random events. I think it has much to do with the shortened telomeres that come with older age. There is an interesting discussion of this on about page 8 of the archives in the MDS thread in this forum. It is worth reading.
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age 70, dx RAEB-2 on 11-26-2013 w/11% blasts. 8 cycles Vidaza 3w/Revlimid. SCT 8/15/2014, relapsed@Day+210 (AML). Now(SCT-Day+1005). Prepping w/ 10 days Dacogen for DLI on 6/9/2017.
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