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Old Sat Dec 6, 2014, 01:29 AM
curlygirl curlygirl is offline
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Join Date: Jun 2013
Posts: 151
MDS, Aplastic Anemia, and Inflammation

I wanted to post this article that I found because, scattered throughout my posts on this thread, you will see that my son had Henoch–Schönlein purpura (a common childhood vasculitis) twice. A more serious course when 6 and a slight relapse when 7, then 6 months after the slight relapse he was diagnosed with Aplastic Anemia. Really, I believe he doesn't have "idiopathic" Aplastic Anemia, he has vasculitis affecting the blood flow into or out of his bone marrow, based on the several body wide symptoms that he had (least of which was that he couldn't control his body temperature. Unless he was on Prednisone it was either 97.5 or 99.5 degrees F - on Prednisone it was 98.6). Imagine a gas tank where you fill the tank with gas, but because of inflammation you pinch the gas line leading either into or out of the bone marrow. If the blood can't get in, or can't get out, the bone marrow can't do what it is supposed to do. We know from a series of tests that inflammation leads his numbers to go down. A series of searches led me to this.

http://link.springer.com/article/10....2247806#page-1

Henoch–Schönlein Purpura as Clinical Presentation of a Myelodysplastic Syndrome.

I know, it's silly, I keep posting random things that I think will come together to form a cohesive "theory of bone marrow failure." Yet recently even the AAMDS facebook page posted a link between Myelodysplastic Syndromes, Autoimmune Diseases, & Inflammation: https://www.facebook.com/aamds

"Moffitt Cancer Center Announces Development of Experimental Treatment for Myelodysplastic Syndromes, Autoimmune Diseases: http://www.marketwatch.com/story/mof...k=MW_news_stmp

Well, hopefully this helps something. I would rather it be all in one place!
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