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started Vidaza - stable after first cycle
Hi All,
I started Vidaza on Nov 12 at a reduced dosage due to low platelets and a low bone marrow cellularity of 10-15%.
My platelets were in the low 20's for several weeks until we started low dose Neumega injections. These were given at 10micrograms/kg (1/5 the normal dosage), after 10 days the platelets were in the 40's.
Reference for Nuemega for MDS patients: http://jco.ascopubs.org/cgi/content/abstract/19/21/4165
After a BMB which identified low cellularity at 10-15% and 8% blasts my doctor decided to start Vidaza at a low dose of 50 gm/m2 for 3 days.
Following the Vidaza week of injections I received Procrit, Neupogen and
Neumega to hold he CBC counts. On day 16 following the injections the counts still remain stable with platelets holding in the 40's. 
The second cycle is planned with a 5 day cycle, starting Dec 8.
My MDS journey with the 3rd drug seems to be starting ok.
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Kirby71, RAEB2 dx 2/04, Thalidomide 30 mo, Revlimid 18 mo, No resp Vidaza
6/09 2nd Thalid use, Promacta, Lowdose Dacogen added 10/09 at 40% blasts. 5/11 BMB-blasts 8%.
2/11 2nd Revl restart=good resp, Platelets drop 6/11, 3rd Thalid,+Nplate+Dacogen. 7/12 Cnts stable for 10 mo.
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