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Second Vidaza Cycle - counts holding
Hi Helen, thanks for the kind words. I hope David is stable or improving.
My 2nd Vidaza cycle of 5 days at 50 mg/m2 started on 12/08/08, my platelets were in the low 40's at the start of the cycle. The platelet count dropped to 21 on 12/22/08. This date corresponds to the 4th day of the 7 day "nadir" period. The nadir is the point of the lowest blood counts (nadir is opposite zenith-high point). A slow increase in the platelet count started on 12/23/08, reaching 25 on 12/26/08. The preliminary data suggests that my body is responding in the "normal" fashion to the Vidaza. Hopefully the counts will increase during the next 9 days until the next Vidaza cycle is scheduled to start. My Hgb has ranged from 11.3 to 9.6 during this time. The WBC has ranged from 5.2 to 1.7, somewhat unstable but responding well to Neupogen.
My doctor has used lots of Procrit, Neupogen and low dose Neumega to stabilize my blood counts following the Vidaza cycle. So far I've taken no transfusions during my 4.8 years treating MDS.
If the Vidaza can control the MDS the counts should all rise as the cycles continue.
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Kirby71, RAEB2 dx 2/04, Thalidomide 30 mo, Revlimid 18 mo, No resp Vidaza
6/09 2nd Thalid use, Promacta, Lowdose Dacogen added 10/09 at 40% blasts. 5/11 BMB-blasts 8%.
2/11 2nd Revl restart=good resp, Platelets drop 6/11, 3rd Thalid,+Nplate+Dacogen. 7/12 Cnts stable for 10 mo.
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