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Hi Susan - Dacogen
My husband completed his second cycle of Dacogen near the end of June. He has said the worst side effect is feeling tired and we know also that his counts should hopefully bottom out this week as they did with the first round. But he is also on a trial of decitabine and tretinoin.
The tretinoin gives him headaches and he is also nauseous during that time, not sure if he feels the need to rest more because it is the week after the decitabine or the effects of the tretinoin.
http://clinicaltrials.gov/ct2/show/NCT00382200
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Debbie, wife of Mike age 58, diagnosed RAEB 2 April 2010. Initial blast count somewhere between 10-15% then 20% after two treatments of Dacogen. Completed induction therapy 8/2/2010. BMB 8/31/10 - 4% blasts. SCT 10/1/2010. Relapsed in 10/2014, second transplant from same donor on 12/31/2014.
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