[Ruth Cuadra]

MaryAlisha,

The reason that they discontinue cyclosporine before a transplant is that it is very hard on the kidneys. The doctor wants it out of your sister's system with some time for her kidneys to recover before the transplant begins. The potential negative effects of the cold-turkey approach are not so important because the entire immune system is about to be replaced anyway. I stopped my cyclosporine abruptly before my transplant and started it again after I got my new bone marrow. It sounds like the new doctor knows what he's doing.

Regards,
Ruth