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Old Mon Feb 15, 2010, 05:31 PM
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Join Date: Mar 2009
Posts: 193
Talking e1905 Clinical Trial w/o MS-275 (Update on Ron's Condition)

Hello Everyone! As promised, I'm providing an update to Ron's ongoing progress while on e1905 Clinical Trial. (Because the first one was Too Long, I've broken it down into two separate Posts...)...

Remember, he is Not in the group that is receiving MS-275 pill.

I last posted 12/03/09 when Ron was having a tough time with a new condition, Prostatitis. We were not happy with his Urologist, and after 30 days of fiddling around with this doctor, we selected a new Urologist and could not be Happier!

Ron's new doctor was able to get Ron's condition under control within a week. Right now, Ron's about 80% better than he was. He continues to have ocassionaly burning after urination, but it's minimal.. as we continue on the treatment with this new Urologist. He and Ron's Hematologist/Oncologist are talking together, discussing the long term plan... The Urologist prescribed the following for Ron's Prostatitis: Levaquin 750mg daily, Q-UROL (Herbal Supplement w/Sawpalmetto), which is sort of like advadart, but, with less side effects. He takes this twice daily, and Celebrex for prostrate inflammation. The Ocologist concurs with this protocol, but, continues to monitor Urologists treatments/status.

Now, an update on Ron's Blood Progress: (I've put the clinical trial cycle number, following by the day of cycle). Ron is on 10-Days of Vidaza injection (low dose), followed by 18 Days off... totally, a 28-Day Cycle.


7Cy-22nd:10/21/09 HGB 14.3, HCT42%,RBC 4.16, WBC 4.2, NEU 37%, PLT136
8Cy-1st:10/28/09 HGB 14.8, HCT43.6%,RBC 4.30, WBC 3.2, NEU 37%, PLT212

8Cy-10th:11/04/09 HGB 14.8, HCT42.8%,RBC 4.24, WBC 3.5,NEU44%, PLT228
** Ron hospitalized on 11/05/09 due to high fever, attributed to Prostatitis.

8Cy-12th:11/06/09 HGB 12.9,HCT 36.8%, RBC 3.61, WBC 3.2, PLT158

8Cy-14th: 11/08/09 HGB 12.3, HCT 34.4%, RBC 3.38, WBC 3.2, PLT90

8Cy-15th: 11/09/09 HGB 12.9, HCT 36.2%, RBC 3.59, WBC 3.0, PLT90

8Cy-16th: 11/10/09 HGB 14.3,HCT40.6%,RBC 4.09, WBC 3.9, NEU57%,PLT107
** Ron released from hospital on 11/10/09.

8Cy-19th:11/13/09 HGB 13.7,HCT40.4%, RBC 3.96,WBC 5.0, NEU41%, PLT132
8Cy-22nd:11/18/09 HGB 13.8,HCT40.7%,RBC 3.93, WBC 3.6, NEU41%, PLT141
9th Cycle: 11/25/09 HGB 14.6,HCT42.9%,RBC4.12, WBC 3.1, NEU38%, PLT185
** Ron’s treatment (Cycle #9) delay for 1 week (personal reasons, will check blood before leaving town. Will resume treatment on 12/09/09.

9th Cycle:11/27/09 HGB 13.7,HCT40.5%,RBC 3.88, WBC 4.7, NEU62%, PLT107
9Cy- 1st: 12/09/09 HGB 13.6,HCT40.5%,RBC 3.89, WBC 6.5, NEU 58%,PLT173
9Cy-10th:12/16/09 HGB 12.8,HCT38.8%,RBC 3.71, WBC 5.4, NEU61%, PLT122

9Cy-15th: 12/23/09 HGB 13.3, HCT38.5%,RBC 3.77,WBC 5.0,NEU58%, PLT102
9Cy-22nd:12/30/09 HGB 13.6, HCT39.9%, RBC 3.88, WBC 3.4,NEU 53%

10Cy-1st:1/06/10 HGB 13.6, HCT39.9%, RBC 3.87, WBC 3.6,NEU52 %, PLT180

10Cy-10th: 1/13/10 (Lab Work Not available for post)

10Cy-15th:1/20/10 HGB 13.7, HCT40.6%, RBC3.87,WBC 4.3,NEU48%, PLT 145
10Cy-22nd:1/27/10 HGB 13.7,HCT40.5%, RBC 3.88, WBC 4.7,NEU62%, PLT107

BMB (2/3/2010): Bone Marrow Biopsy- Treatment Delayed 1 week

Labs 2/3/10: HGB 13.6, HCT 39.7%, RBC 3.83, WBC 3.6, NEU 47%, PLT168

11Cy-1st: 2/10/10 HGB 14.0,HCT 41.7%, RBC 4.02, WBC 3.3, PLT219


Please see next post for updated status... Cindy
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