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Treatment
Hi CCNarayanan,
My mother has a similar diagnosis as your father, though she has cytopenia(low count) in the red cells only, her bone marrow showed dysplasia in all 3 lines, therefore RCMD diagnosis.
I would agree with Birgitta-A's advice to try aranesp for few weeks, given his low initial epo level, he may respond. Decitabine is a harsh treatment, and as I understand we do not have the option of Vidaza treatment in India.
When a patient gets blood transfusions, we do not get to know the patients own Hb level correctly. Has his blood transfusion requirement increased over last 6 months? Given his age and not-so-high transfusion requirement, I would like to understand what makes your doctor suggest Decitabine. Is it because of the monosomy 7 and del7q31 or is he seeing a progression of the disease?
Do keep us posted on the progress. All the best.
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Mother age 79, dx MDS RCMD low risk del 20q April 2013, no response to EPO, Danazol. pRBC tx dependent - 2 units every 3-4 weeks, exjade Dec 2013 - Mar2014, restarted Dec 2014
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