Excellent explanation, Lisa. There are a few other comments about chromosome changes in the
Chances of AA turning onto MDS thread.
One minor correction: "5q minus" or "5q-" refers to a specific deletion in the long arm of chromosome 5. It affects bone marrow and is associated with MDS and with acute myeloid leukemia (AML).
There's a corresponding "5p minus" or "5p-" for deletion of part of the short arm of chromosome 5, but it's not associated with bone marrow failure diseases.