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Old Tue Nov 21, 2017, 04:15 PM
Hopeful Hopeful is offline
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Join Date: Jan 2009
Location: California, USA
Posts: 766
Hi Sarah,

I would insist on another BMB and more frequent blood testing. A significant drop in platelets is a sign of a relapse, and 103k is a significant drop! (40k is pretty significant as well.)

Sometimes restarting cyclosporine can prevent a full-blown relapse. Were you restarted on a full dose? If cyclosporine can't turn things around, you will likely have to go through rATG again.

I wouldn't think of this as your body rejecting the medicine. You may be one of the people that requires cyclosporine to maintain your counts.

Sorry this is happening. Hopefully the cyclosporine will work.
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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